SCHEMBL850574

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15651212	0.85	ALDH1A1 (0.58)	HSP90AA1HSP90AB1HPGDALDH1A1TP53
	SCHEMBL9300442	0.84	HPGD (0.71)	HPGDALDH1A1TP53TSHRMGLL
	SCHEMBL848798	0.84	HPGD (0.77)	HPGDALDH1A1TP53TSHRMGLL
	SCHEMBL12217952	0.84	HSP90AA1 (0.68)	HSP90AA1HSP90AB1HPGDALDH1A1TP53
	SCHEMBL848035	0.83	HPGD (0.51)	HSP90AA1HSP90AB1HPGDALDH1A1TP53
	SCHEMBL2378485	0.83	HPGD (0.77)	HPGDALDH1A1TP53TSHRCNR2
	SCHEMBL2376496	0.83	HPGD (0.77)	HPGDALDH1A1TP53TSHRCNR2
	SCHEMBL21201347	0.82	HSP90AA1 (0.56)	HSP90AA1HSP90AB1HPGDTSHRLRRK2
	SCHEMBL849340	0.82	HPGD (0.59)	HPGDALDH1A1TP53TSHRMGLL
	SCHEMBL9997035	0.82	KMT2A (0.55)	HSP90AA1HSP90AB1HPGDALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.