Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | DRD1 | P21728 | 4/20 | 0.36 |
| ▸ | DRD3 | P35462 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | PTAFR | P25105 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8483898 | 0.95 | DRD1 (0.37) | ALDH1A1GAASMN1; SMN2PDE4BDRD2 | |
| SCHEMBL8480397 | 0.94 | PDE4B (0.38) | ALDH1A1GAASMN1; SMN2PDE4BDRD2 | |
| SCHEMBL8484473 | 0.93 | PDE4B (0.39) | PDE4BDRD2DRD1DRD3SIGMAR1 | |
| SCHEMBL8480345 | 0.93 | PDE4B (0.39) | PDE4BDRD2DRD1DRD3SIGMAR1 | |
| SCHEMBL8484446 | 0.93 | PDE4B (0.39) | PDE4BDRD2DRD1DRD3SIGMAR1 | |
| SCHEMBL8487323 | 0.93 | PDE4B (0.39) | PDE4BDRD2DRD1DRD3SIGMAR1 | |
| SCHEMBL8482498 | 0.91 | ALDH1A1 (0.40) | ALDH1A1GAASMN1; SMN2DRD1DRD3 | |
| SCHEMBL8479425 | 0.90 | PDE4B (0.37) | ALDH1A1GAASMN1; SMN2PDE4BDRD2 | |
| 6,8-Dimethoxy-3,7-Dimethylisochroman SCHEMBL8479086 | 0.86 | ATM (0.41) | ALDH1A1GAASMN1; SMN2DRD1KDM4E | |
| SCHEMBL8482920 | 0.85 | HTR2A (0.38) | PDE4BDRD2DRD1DRD3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922889-A | REACTING 3,7-DIMETHYL-6,8-DIMETHOXYISOCHROMAN WITH SODIUM ETHYL THIOLATE OR SODIUM HYDRIDE TO PRODUCE 3,7-DIMETHYL-6-HYDROXY-8-METHOXYISOCHROMAN; POSSESS PHYTOTOXIC ACTIVITY USED AS A BIODEGRADABLE HERBICIDE | THE UNITED STATES OD AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1999-07-13 | — | — | US | claimed |
| US-5922889-A | REACTING 3,7-DIMETHYL-6,8-DIMETHOXYISOCHROMAN WITH SODIUM ETHYL THIOLATE OR SODIUM HYDRIDE TO PRODUCE 3,7-DIMETHYL-6-HYDROXY-8-METHOXYISOCHROMAN; POSSESS PHYTOTOXIC ACTIVITY USED AS A BIODEGRADABLE HERBICIDE | THE UNITED STATES OD AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1999-07-13 | — | — | US | disclosed |