Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 5/20 | 0.39 |
| ▸ | DRD3 | P35462 | 5/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.37 |
| ▸ | HTR2C | P28335 | 4/20 | 0.37 |
| ▸ | HTR2B | P41595 | 4/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8487323 | 1.00 | PDE4B (0.39) | PDE4BDRD1DRD3DRD2PDE4D | |
| SCHEMBL8484446 | 1.00 | PDE4B (0.39) | PDE4BDRD1DRD3DRD2PDE4D | |
| SCHEMBL8484473 | 1.00 | PDE4B (0.39) | PDE4BDRD1DRD3DRD2PDE4D | |
| SCHEMBL8480397 | 0.99 | PDE4B (0.38) | PDE4BDRD1DRD3DRD2PDE4D | |
| SCHEMBL8483898 | 0.95 | DRD1 (0.37) | PDE4BDRD1DRD3DRD2PDE4D | |
| SCHEMBL8480217 | 0.93 | ALDH1A1 (0.39) | PDE4BDRD1DRD3DRD2SIGMAR1 | |
| SCHEMBL8479889 | 0.91 | HTR2A (0.39) | PDE4BDRD1DRD3DRD2PDE4D | |
| SCHEMBL8484395 | 0.91 | HTR2A (0.39) | PDE4BDRD1DRD3DRD2PDE4D | |
| SCHEMBL8486253 | 0.91 | HTR2A (0.39) | PDE4BDRD1DRD3DRD2PDE4D | |
| SCHEMBL8480861 | 0.91 | HTR2A (0.39) | PDE4BDRD1DRD3DRD2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922889-A | REACTING 3,7-DIMETHYL-6,8-DIMETHOXYISOCHROMAN WITH SODIUM ETHYL THIOLATE OR SODIUM HYDRIDE TO PRODUCE 3,7-DIMETHYL-6-HYDROXY-8-METHOXYISOCHROMAN; POSSESS PHYTOTOXIC ACTIVITY USED AS A BIODEGRADABLE HERBICIDE | THE UNITED STATES OD AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1999-07-13 | — | — | US | disclosed |