Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44837 | 0.81 | IDO1 (0.57) | IDO1KDM4EKMT2AMAOBPOLQ | |
| SCHEMBL29389277 | 0.81 | IDO1 (0.57) | IDO1KDM4EKMT2AMAOBPOLQ | |
| SCHEMBL408969 | 0.78 | ALDH1A1 (0.39) | IDO1PDK2KDM4EMEN1KMT2A | |
| SCHEMBL10563090 | 0.78 | APOBEC3G (0.44) | PDK2KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL1607338 | 0.78 | AKR1B1 (0.42) | IDO1PTGS2PDK2 | |
| SCHEMBL30368290 | 0.78 | IDO1 (0.41) | IDO1PTGS2PDK2KDM4EMEN1 | |
| SCHEMBL542693 | 0.78 | IDO1 (0.41) | IDO1PTGS2PDK2KDM4EMEN1 | |
| SCHEMBL737569 | 0.76 | PDCD1 (0.48) | IDO1KDM4EPOLQALDH1A1TDP1 | |
| SCHEMBL3283101 | 0.76 | P2RX7 (0.44) | TRPV1 | |
| SCHEMBL456789 | 0.76 | IDO1 (0.44) | IDO1PDK2KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856334-A | ANTAGONIST FOR EOSINOPHILS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-05 | — | — | US | disclosed |
| EP-0773219-A1 | IMIDAZOQUINOLINE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-14 | — | — | EP | disclosed |