Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | UGCG | Q16739 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8483481 | 0.89 | KDM4E (0.48) | KDM4EGAAHTTGLAHPGD | |
| SCHEMBL8487682 | 0.88 | KDM4E (0.58) | KDM4EGAAHTTGLAHPGD | |
| SCHEMBL8484042 | 0.85 | KDM4E (0.52) | KDM4EHPGDALDH1A1 | |
| SCHEMBL8482120 | 0.81 | KDM4E (0.57) | KDM4EGAAHTTGLAALDH1A1 | |
| SCHEMBL9685709 | 0.80 | KDM4E (0.46) | KDM4EHPGDALDH1A1NQO2 | |
| SCHEMBL8487677 | 0.79 | CYP1A2 (0.46) | KDM4EGAAHPGDALDH1A1LMNA | |
| SCHEMBL7498546 | 0.79 | KDM4E (0.51) | KDM4EGAAHTTGLAHPGD | |
| SCHEMBL8484525 | 0.79 | NQO2 (0.44) | KDM4EGAAHTTGLAHPGD | |
| SCHEMBL7495661 | 0.77 | KDM4E (0.48) | KDM4EGAAHTTGLAHPGD | |
| SCHEMBL2833853 | 0.73 | KDM4E (1.00) | KDM4EGAAHTTGLAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914402-A | Process for preparing 1-aryl-4-oxopyrrolo 3,2-c! quinoline derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1999-06-22 | — | — | US | disclosed |