Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 2/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8487682 | 0.92 | KDM4E (0.58) | KDM4EALDH1A1GLAGAAHTT | |
| SCHEMBL8484042 | 0.91 | KDM4E (0.52) | KDM4EALDH1A1 | |
| SCHEMBL9686536 | 0.88 | DDB1 (0.48) | KDM4E | |
| SCHEMBL9685709 | 0.86 | KDM4E (0.46) | KDM4EALDH1A1TNKSTNKS2PARP10 | |
| SCHEMBL7498546 | 0.85 | KDM4E (0.51) | KDM4EALDH1A1GLAGAAHTT | |
| SCHEMBL7495661 | 0.83 | KDM4E (0.48) | KDM4EALDH1A1GLAGAAHTT | |
| SCHEMBL8481514 | 0.83 | CYP1A2 (0.43) | GAA | |
| SCHEMBL8484525 | 0.81 | NQO2 (0.44) | KDM4EALDH1A1GLAGAAHTT | |
| SCHEMBL8487677 | 0.81 | CYP1A2 (0.46) | KDM4EALDH1A1GAA | |
| SCHEMBL8071575 | 0.81 | KDM4E (0.41) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914402-A | Process for preparing 1-aryl-4-oxopyrrolo 3,2-c! quinoline derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1999-06-22 | — | — | US | disclosed |