Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 4/20 | 0.56 |
| ▸ | KCNQ1 | P51787 | 4/20 | 0.56 |
| ▸ | ABCC9 | O60706 | 13/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8480778 | 0.88 | KCNE1 (0.57) | KCNE1KCNQ1ABCC9 | |
| SCHEMBL8476342 | 0.83 | KCNE1 (0.49) | KCNE1KCNQ1ABCC9 | |
| SCHEMBL8479222 | 0.80 | KCNE1 (0.49) | KCNE1KCNQ1ABCC9 | |
| SCHEMBL7464213 | 0.78 | KCNE1 (0.52) | KCNE1KCNQ1ABCC9 | |
| SCHEMBL8476346 | 0.76 | KCNE1 (0.50) | KCNE1KCNQ1ABCC9 | |
| SCHEMBL8476661 | 0.73 | KCNA5 (0.46) | KCNE1KCNQ1 | |
| SCHEMBL8480774 | 0.73 | KCNE1 (0.60) | KCNE1KCNQ1ABCC9 | |
| SCHEMBL7477965 | 0.73 | KCNE1 (0.60) | KCNE1KCNQ1ABCC9 | |
| SCHEMBL13825287 | 0.73 | KCNE1 (0.56) | KCNE1KCNQ1ABCC9 | |
| SCHEMBL9032544 | 0.72 | KCNE1 (0.56) | KCNE1KCNQ1ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955607-A | TREATING CARDIOVASCULAR AND GASTROINTESTINAL DISORDERS | HOECHST MARION ROUSSEL DEUTSCHLAND (DE) | 1999-09-21 | — | — | US | disclosed |