Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 3/20 | 0.50 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.50 |
| ▸ | ABCC9 | O60706 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8480778 | 0.85 | KCNE1 (0.57) | KCNE1KCNQ1ABCC9 | |
| SCHEMBL8479297 | 0.76 | KCNE1 (0.51) | KCNE1KCNQ1ABCC9KDM4EALDH1A1 | |
| SCHEMBL8480771 | 0.76 | KCNE1 (0.56) | KCNE1KCNQ1ABCC9 | |
| SCHEMBL8476342 | 0.75 | KCNE1 (0.49) | KCNE1KCNQ1ABCC9 | |
| SCHEMBL8479222 | 0.70 | KCNE1 (0.49) | KCNE1KCNQ1ABCC9 | |
| SCHEMBL8479300 | 0.68 | KCNE1 (0.71) | KCNE1KCNQ1ABCC9KDM4ECYP3A4 | |
| SCHEMBL7464213 | 0.68 | KCNE1 (0.52) | KCNE1KCNQ1ABCC9CYP3A4 | |
| SCHEMBL13825287 | 0.68 | KCNE1 (0.56) | KCNE1KCNQ1ABCC9 | |
| SCHEMBL10885309 | 0.67 | ABCC9 (0.60) | KCNE1KCNQ1ABCC9 | |
| SCHEMBL9032549 | 0.67 | KCNE1 (0.56) | KCNE1KCNQ1ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955607-A | TREATING CARDIOVASCULAR AND GASTROINTESTINAL DISORDERS | HOECHST MARION ROUSSEL DEUTSCHLAND (DE) | 1999-09-21 | — | — | US | disclosed |