Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.46 |
| ▸ | CDC25A | P30304 | 2/20 | 0.44 |
| ▸ | CDC25B | P30305 | 2/20 | 0.44 |
| ▸ | CDC25C | P30307 | 2/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8484634 | 0.83 | KDM4E (0.50) | CYP19A1CDC25ACDC25BCDC25CDUSP3 | |
| SCHEMBL8483385 | 0.79 | KDM4E (0.45) | CYP19A1CDC25ACDC25BCDC25CDUSP3 | |
| SCHEMBL8479782 | 0.77 | KDM4E (0.43) | CYP19A1CDC25ACDC25BCDC25CDUSP3 | |
| SCHEMBL8486969 | 0.76 | KDM4E (0.46) | CYP19A1CDC25ACDC25BCDC25CDUSP3 | |
| SCHEMBL8486372 | 0.72 | CDC25A (0.72) | CYP19A1CDC25ACDC25BCDC25CDUSP3 | |
| SCHEMBL8485576 | 0.72 | KDM4E (0.47) | CYP19A1CDC25ACDC25BCDC25CDUSP3 | |
| SCHEMBL8480229 | 0.72 | KDM4E (0.47) | CYP19A1CDC25ACDC25BCDC25CDUSP3 | |
| SCHEMBL8524349 | 0.71 | CDC25A (0.59) | CYP19A1CDC25ACDC25BCDC25CDUSP3 | |
| SCHEMBL8524907 | 0.71 | KDM4E (0.49) | CYP19A1CDC25ACDC25BCDC25CDUSP3 | |
| SCHEMBL8484951 | 0.70 | KDM4E (0.48) | CYP19A1CDC25ACDC25BCDC25CDUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |