Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | AR | P10275 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | BCL2 | P10415 | 2/20 | 0.41 |
| ▸ | BAX | Q07812 | 2/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | CDC25C | P30307 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8483385 | 0.85 | KDM4E (0.45) | KDM4EARKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL8479782 | 0.84 | KDM4E (0.43) | KDM4EARKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL8484634 | 0.82 | KDM4E (0.50) | KDM4EARKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL8480783 | 0.76 | CYP19A1 (0.46) | KDM4EARKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL17875110 | 0.72 | MET (0.44) | KMT2ACDK5CDK5R1CDC25ACDC25B | |
| SCHEMBL8486372 | 0.71 | CDC25A (0.72) | KDM4EARKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL8485576 | 0.70 | KDM4E (0.47) | KDM4EARKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL8524349 | 0.70 | CDC25A (0.59) | KDM4EARSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8524907 | 0.70 | KDM4E (0.49) | KDM4EARKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL8484951 | 0.69 | KDM4E (0.48) | KDM4EARKMT2ASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |