Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 15/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | MASP2 | O00187 | 1/20 | 0.38 |
| ▸ | CCR4 | P51679 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7019802 | 0.91 | F2 (0.63) | F2PRSS1PRSS2PRSS3MASP2 | |
| SCHEMBL7025567 | 0.91 | F2 (0.62) | F2PRSS1PRSS2PRSS3MASP2 | |
| SCHEMBL7992846 | 0.86 | F2 (0.60) | F2PRSS1PRSS2PRSS3MASP2 | |
| SCHEMBL7026174 | 0.86 | F2 (0.60) | F2PRSS1PRSS2PRSS3MASP2 | |
| SCHEMBL7021980 | 0.79 | F2 (0.62) | F2PRSS1PRSS2PRSS3MASP2 | |
| SCHEMBL7022027 | 0.79 | F2 (0.48) | F2PRSS1PRSS2PRSS3MASP2 | |
| SCHEMBL7024780 | 0.79 | F2 (0.62) | F2PRSS1PRSS2PRSS3MASP2 | |
| SCHEMBL7030821 | 0.78 | F2 (0.63) | F2PRSS1PRSS2PRSS3MASP2 | |
| SCHEMBL7021036 | 0.78 | F2 (0.60) | F2PRSS1PRSS2PRSS3MASP2 | |
| SCHEMBL7023629 | 0.74 | F2 (0.46) | F2PRSS1PRSS2PRSS3MASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997474-B1 | Antithrombotic agents | PFIZER (US) | 2003-10-29 | — | — | EP | disclosed |