Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 15/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.41 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.41 |
| ▸ | CTSD | P07339 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476969 | 0.84 | TRPV1 (0.36) | TRPV1CTSDBACE1 | |
| SCHEMBL8480422 | 0.82 | TRPV1 (0.50) | TRPV1CYP3A4KCNE1KCNQ1CTSD | |
| SCHEMBL8482068 | 0.81 | TSHR (0.42) | TRPV1CYP3A4 | |
| SCHEMBL6558672 | 0.78 | TRPV1 (0.49) | TRPV1CYP3A4KCNE1KCNQ1CTSD | |
| SCHEMBL8477265 | 0.77 | TRPV1 (0.49) | TRPV1CYP3A4KCNE1KCNQ1CTSD | |
| SCHEMBL8476718 | 0.77 | TRPV1 (0.38) | TRPV1CTSDBACE1 | |
| SCHEMBL6560804 | 0.76 | TRPV1 (0.48) | TRPV1CYP3A4KCNE1KCNQ1CTSD | |
| SCHEMBL7828519 | 0.75 | TRPV1 (0.45) | TRPV1CYP3A4KCNE1KCNQ1CTSD | |
| SCHEMBL6559589 | 0.74 | TRPV1 (0.52) | TRPV1CYP3A4KCNE1KCNQ1 | |
| Guanidine SCHEMBL8525006 | 0.73 | TRPV1 (0.35) | TRPV1CTSDBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955607-A | TREATING CARDIOVASCULAR AND GASTROINTESTINAL DISORDERS | HOECHST MARION ROUSSEL DEUTSCHLAND (DE) | 1999-09-21 | — | — | US | disclosed |