Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21389247 | 0.92 | TSHR (0.48) | ADRA1AHIF1AKDM4EMAPK1TSHR | |
| SCHEMBL18649603 | 0.79 | KDM4E (0.54) | ADRA1AHIF1AKDM4EMAPK1TSHR | |
| SCHEMBL8432779 | 0.77 | KDM4E (0.52) | ADRA1AHIF1AKDM4EMAPK1TSHR | |
| SCHEMBL22497757 | 0.76 | CYP2D6 (0.43) | ADRA1AHIF1AMAPK1CYP2D6GAA | |
| SCHEMBL11193449 | 0.76 | TSHR (0.71) | ADRA1AHIF1AKDM4EMAPK1TSHR | |
| SCHEMBL14010469 | 0.75 | KDM4E (0.67) | ADRA1AHIF1AKDM4EMAPK1TSHR | |
| SCHEMBL24795949 | 0.75 | CYP2D6 (0.50) | HIF1AKDM4ETSHRCYP2D6GAA | |
| SCHEMBL1900471 | 0.74 | KDM4E (0.82) | ADRA1AHIF1AKDM4EMAPK1TSHR | |
| SCHEMBL25935846 | 0.74 | CYP2D6 (0.55) | HIF1AKDM4ETSHRCYP2D6GAA | |
| SCHEMBL21389151 | 0.74 | CYP2D6 (0.40) | HIF1AKDM4ECYP2D6GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004531-A | LIGANDS FOR RADIOPHARMACEUTICALS; CAPABLE OF CHELATING RADIOMETAL SPECIES AND OF BEING BOUND TO BIOLOGICAL TARGETING MOLECULES | NYCOMED AMERSHAM PLC (GB) | 1999-12-21 | — | — | US | disclosed |