Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | FABP3 | P05413 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21389247 | 0.77 | TSHR (0.48) | CYP2D6HIF1AGAAKDM4EL3MBTL1 | |
| SCHEMBL6753707 | 0.74 | MEN1 (0.52) | MEN1KMT2ADNM1 | |
| SCHEMBL8480919 | 0.74 | ADRA1A (0.48) | CYP2D6HIF1AGAAKDM4EL3MBTL1 | |
| SCHEMBL15292955 | 0.72 | KDM4E (0.48) | HIF1AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12522966 | 0.72 | DNM1 (0.43) | HIF1AGAAKDM4EALDH1A1LMNA | |
| SCHEMBL21389172 | 0.71 | DNM1 (0.31) | DNM1 | |
| SCHEMBL24795949 | 0.71 | CYP2D6 (0.50) | CYP2D6HIF1AGAAKDM4EL3MBTL1 | |
| SCHEMBL25935846 | 0.70 | CYP2D6 (0.55) | CYP2D6HIF1AGAAKDM4EL3MBTL1 | |
| SCHEMBL13075426 | 0.69 | DNM1 (0.62) | ALDH1A1DNM1 | |
| SCHEMBL21558203 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183577-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |