Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8482948 | 0.89 | HTT (0.37) | L3MBTL1LMNAMAPTALDH1A1GAA | |
| SCHEMBL8482590 | 0.89 | ALDH1A1 (0.37) | L3MBTL1POLBLMNAMAPTALDH1A1 | |
| SCHEMBL8481725 | 0.88 | HDAC4 (0.46) | L3MBTL1POLBCNR1CNR2KMT2A | |
| SCHEMBL8481390 | 0.88 | CNR1 (0.45) | L3MBTL1POLBLMNAMAPTALDH1A1 | |
| SCHEMBL8478498 | 0.87 | HDAC4 (0.45) | L3MBTL1POLBLMNAMAPTCNR1 | |
| SCHEMBL8482561 | 0.87 | MEN1 (0.47) | LMNAMAPTALDH1A1GAACNR1 | |
| SCHEMBL8478024 | 0.86 | ALDH1A1 (0.44) | L3MBTL1LMNAALDH1A1GAACNR1 | |
| SCHEMBL8477772 | 0.85 | HAO1 (0.38) | LMNAALDH1A1KMT2AMEN1HTT | |
| SCHEMBL8478094 | 0.84 | ALDH1A1 (0.36) | L3MBTL1POLBLMNAMAPTALDH1A1 | |
| SCHEMBL8479404 | 0.84 | PTPN1 (0.45) | CNR2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932765-A | REDUCTASE INHIBITORS | MERCK PATENT GESELLSCHAFT MIT (DE) | 1999-08-03 | — | — | US | disclosed |