Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8480948 | 0.86 | L3MBTL1 (0.42) | ALDH1A1L3MBTL1KMT2AMEN1CNR1 | |
| SCHEMBL8481390 | 0.85 | CNR1 (0.45) | ALDH1A1L3MBTL1KMT2AMEN1CNR1 | |
| SCHEMBL8482561 | 0.84 | MEN1 (0.47) | ALDH1A1KMT2AMEN1CNR1CNR2 | |
| SCHEMBL8478498 | 0.84 | HDAC4 (0.45) | L3MBTL1KMT2AMEN1CNR1CNR2 | |
| SCHEMBL8482590 | 0.83 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1KMT2AMEN1CNR1 | |
| SCHEMBL28511885 | 0.83 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1KMT2AMEN1GSK3B | |
| SCHEMBL8477772 | 0.81 | HAO1 (0.38) | ALDH1A1KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL8479404 | 0.81 | PTPN1 (0.45) | CNR2GSK3BHDAC1HDAC8MMP1 | |
| SCHEMBL8477689 | 0.80 | MEN1 (0.44) | KMT2AMEN1CNR1CNR2HDAC4 | |
| SCHEMBL8478094 | 0.79 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1KMT2AMEN1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932765-A | REDUCTASE INHIBITORS | MERCK PATENT GESELLSCHAFT MIT (DE) | 1999-08-03 | — | — | US | disclosed |