Phenidone

Phenidone

SCHEMBL8480957

O=C1CCN(c2ccccc2)N1.[NaH]

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 15/20 0.96
G6PD P11413 1/20 0.96
ALOX15 P16050 1/20 0.96
ALOX12 P18054 1/20 0.96
PTGS1 P23219 1/20 0.96
PTGS2 P35354 1/20 0.96
DDB1 Q16531 1/20 0.52
CRBN Q96SW2 1/20 0.52
GAA P10253 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenidone SCHEMBL10904906 0.98 ALOX5 (1.00) ALOX5G6PDALOX15ALOX12PTGS1
Phenidone SCHEMBL235192 0.98 ALOX5 (1.00) ALOX5G6PDALOX15ALOX12PTGS1
Phenidone SCHEMBL9281777 0.94 ALOX5 (0.92) ALOX5G6PDALOX15ALOX12PTGS1
Phenidone SCHEMBL6653725 0.89 ALOX5 (0.83) ALOX5G6PDALOX15ALOX12PTGS1
Phenidone SCHEMBL8171039 0.89 ALOX5 (0.83) ALOX5G6PDALOX15ALOX12PTGS1
Phenidone SCHEMBL8171314 0.89 ALOX5 (0.83) ALOX5G6PDALOX15ALOX12PTGS1
Phenidone SCHEMBL11130362 0.89 ALOX5 (0.83) ALOX5G6PDALOX15ALOX12PTGS1
Phenidone SCHEMBL7999908 0.88 ALOX5 (0.80) ALOX5G6PDALOX15ALOX12PTGS1
Phenidone SCHEMBL8470486 0.88 ALOX5 (0.80) ALOX5G6PDALOX15ALOX12PTGS1
Phenidone SCHEMBL7999902 0.88 ALOX5 (0.80) ALOX5G6PDALOX15ALOX12PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5981138-A PHOTOSENSITIVE PHOTOGRAPHIC MATERIAL CONTAINS A MESOIONIC RING CONTAINING HYDRAZINE COMPOUND; STABILITY AND EXCELLENT STORABILITY FUJI PHOTO FILM CO., LTD. (JP) 1999-11-09 US disclosed