Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 3/20 | 0.49 |
| ▸ | F10 | P00742 | 3/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8484720 | 0.88 | NOD2 (0.54) | CCR2F10NOD2NOD1AR | |
| SCHEMBL8483705 | 0.87 | CCR2 (0.51) | CCR2F10NOD2NOD1PLA2G2A | |
| SCHEMBL17060318 | 0.81 | NOD2 (0.60) | CCR2F10NOD2NOD1PLA2G2A | |
| SCHEMBL5424592 | 0.78 | NOD2 (0.75) | CCR2F10NOD2NOD1AR | |
| SCHEMBL8602230 | 0.78 | ADRB3 (0.45) | CCR2F10 | |
| SCHEMBL8602233 | 0.78 | ADRB3 (0.45) | CCR2F10 | |
| SCHEMBL18746289 | 0.78 | CCR2 (0.54) | CCR2F10NOD2NOD1PLA2G2A | |
| SCHEMBL8603639 | 0.77 | CCR2 (0.39) | CCR2F10NOD2NOD1PLA2G2A | |
| SCHEMBL8603638 | 0.77 | CCR2 (0.39) | CCR2F10NOD2NOD1PLA2G2A | |
| SCHEMBL17060361 | 0.76 | CCR2 (0.57) | CCR2F10NOD2NOD1PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859044-A | TREATING DIABETES, HYPERGLYCEMIA, OBESITY; INCREASING CONTENT OF LEAN MEAT IN ANIMALS | PFIZER INC. (US) | 1999-01-12 | — | — | US | disclosed |
| EP-0822185-A1 | B-3-adrenergic agonists as antidiabetic and antiobesity agents | PFIZER INC. (US) | 1998-02-04 | — | — | EP | disclosed |