Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 13/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | ECE1 | P42892 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476611 | 0.88 | TRPV1 (0.49) | TRPV1CYP3A4HTT | |
| SCHEMBL8482068 | 0.86 | TSHR (0.42) | TRPV1CYP3A4HTTATMTSHR | |
| SCHEMBL8482576 | 0.85 | TRPV1 (0.49) | TRPV1CYP3A4 | |
| SCHEMBL8480649 | 0.80 | TRPV1 (0.47) | TRPV1CYP3A4 | |
| SCHEMBL8481888 | 0.80 | TRPV1 (0.50) | TRPV1CYP3A4 | |
| SCHEMBL8477642 | 0.79 | TRPV1 (0.42) | TRPV1CYP3A4HTTATMSMN1; SMN2 | |
| SCHEMBL8480422 | 0.79 | TRPV1 (0.50) | TRPV1CYP3A4 | |
| SCHEMBL8476363 | 0.79 | TRPV1 (0.47) | TRPV1CYP3A4 | |
| SCHEMBL8477265 | 0.79 | TRPV1 (0.49) | TRPV1CYP3A4 | |
| SCHEMBL8481389 | 0.78 | TRPV1 (0.44) | TRPV1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955607-A | TREATING CARDIOVASCULAR AND GASTROINTESTINAL DISORDERS | HOECHST MARION ROUSSEL DEUTSCHLAND (DE) | 1999-09-21 | — | — | US | disclosed |