Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8480649 | 0.81 | TRPV1 (0.47) | TRPV1CYP3A4ALDH1A1 | |
| SCHEMBL8476363 | 0.81 | TRPV1 (0.47) | TRPV1LMNACYP3A4ALDH1A1 | |
| SCHEMBL8476611 | 0.80 | TRPV1 (0.49) | TRPV1CYP3A4HTTALDH1A1 | |
| SCHEMBL8481963 | 0.79 | TRPV1 (0.44) | TRPV1CYP3A4HTTSMN1; SMN2ATM | |
| Hydrochloric Acid SCHEMBL8481795 | 0.79 | TRPV1 (0.46) | TRPV1CYP3A4ALDH1A1 | |
| SCHEMBL8481888 | 0.79 | TRPV1 (0.50) | TRPV1CYP3A4 | |
| SCHEMBL8482576 | 0.78 | TRPV1 (0.49) | TRPV1CYP3A4 | |
| SCHEMBL7467409 | 0.78 | L3MBTL1 (0.42) | L3MBTL1POLBLMNAKCNH2ALOX15 | |
| SCHEMBL8480422 | 0.78 | TRPV1 (0.50) | TRPV1CYP3A4 | |
| SCHEMBL8476544 | 0.77 | TRPV1 (0.44) | TRPV1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955607-A | TREATING CARDIOVASCULAR AND GASTROINTESTINAL DISORDERS | HOECHST MARION ROUSSEL DEUTSCHLAND (DE) | 1999-09-21 | — | — | US | disclosed |