Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8482120 | 0.88 | KDM4E (0.57) | KDM4E | |
| SCHEMBL8484042 | 0.88 | KDM4E (0.52) | KDM4E | |
| SCHEMBL8485221 | 0.86 | KDM4E (0.38) | KDM4E | |
| SCHEMBL8071575 | 0.85 | KDM4E (0.41) | KDM4E | |
| SCHEMBL8481514 | 0.84 | CYP1A2 (0.43) | — | |
| SCHEMBL9685709 | 0.83 | KDM4E (0.46) | KDM4E | |
| SCHEMBL7488966 | 0.82 | ADRA1D (0.42) | KDM4E | |
| SCHEMBL8066947 | 0.81 | KDM4E (0.38) | KDM4E | |
| SCHEMBL8487682 | 0.79 | KDM4E (0.58) | KDM4E | |
| SCHEMBL7489494 | 0.77 | KDM4E (0.40) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307078-B1 | QUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1992-08-26 | — | — | EP | disclosed |
| US-5051508-A | Antisecretory agents and enzyme inhibitors as antiulcer agents | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1991-09-24 | — | — | US | disclosed |
| EP-0307078-A1 | Quinoline derivatives, process for their preparation and pharmaceutical compositions containing them | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1989-03-15 | — | — | EP | disclosed |