Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8480729 | 0.93 | LMNA (0.53) | LMNATSHRALDH1A1HSD17B10CFTR | |
| SCHEMBL8482141 | 0.86 | LMNA (0.47) | LMNATSHRALDH1A1HSD17B10CFTR | |
| SCHEMBL8477921 | 0.84 | ALDH1A1 (0.55) | TSHRALDH1A1HSD17B10MAPTALOX15 | |
| SCHEMBL8482147 | 0.79 | HTT (0.54) | TSHRALDH1A1HSD17B10MAPTKMT2A | |
| SCHEMBL28424016 | 0.78 | TSHR (0.50) | LMNATSHRALDH1A1HSD17B10CFTR | |
| SCHEMBL316591 | 0.77 | LMNA (0.53) | LMNATSHRALDH1A1HSD17B10CFTR | |
| SCHEMBL22481057 | 0.77 | LMNA (0.53) | LMNATSHRALDH1A1HSD17B10CFTR | |
| SCHEMBL40534 | 0.77 | ALDH1A1 (0.64) | LMNATSHRALDH1A1HSD17B10CFTR | |
| Dimethyl Phthalate SCHEMBL9436120 | 0.77 | ALDH1A1 (0.64) | LMNATSHRALDH1A1HSD17B10CFTR | |
| SCHEMBL31440979 | 0.77 | ALDH1A1 (0.64) | LMNATSHRALDH1A1HSD17B10CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856334-A | ANTAGONIST FOR EOSINOPHILS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-05 | — | — | US | disclosed |
| EP-0773219-A1 | IMIDAZOQUINOLINE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-14 | — | — | EP | disclosed |