SCHEMBL8482159

SCHEMBL8482159

Fc1cc2ccc1c1c(C(F)(F)F)[c]ccc21

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8484183 0.81 ALDH1A1 (0.32)
SCHEMBL7450361 0.81 NT5E (0.31)
SCHEMBL7401015 0.80
SCHEMBL7404087 0.78
SCHEMBL8484520 0.75
SCHEMBL8482715 0.73
SCHEMBL8482018 0.71
SCHEMBL8477765 0.71 CA12 (0.30)
SCHEMBL8478282 0.70 KDM4E (0.31)
SCHEMBL6067185 0.67 HPRT1 (0.50) HPRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5939418-A ANTICOAGULANT THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1999-08-17 US disclosed