Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 7/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 2/20 | 0.33 |
| ▸ | UGCG | Q16739 | 2/20 | 0.33 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8481007 | 0.74 | DRD4 (0.41) | DRD4SLC6A3KMT2A | |
| SCHEMBL8434603 | 0.71 | ADORA2A (0.43) | DRD4DRD2DRD3 | |
| SCHEMBL27828848 | 0.71 | ADORA2A (0.43) | DRD4DRD2DRD3 | |
| SCHEMBL8480377 | 0.71 | ADORA2A (0.43) | DRD4DRD2DRD3 | |
| SCHEMBL8482174 | 0.68 | HRH3 (0.38) | DRD4SLC6A2SLC6A4SLC6A3DRD2 | |
| SCHEMBL8482170 | 0.68 | HRH3 (0.38) | DRD4SLC6A2SLC6A4SLC6A3DRD2 | |
| SCHEMBL8481010 | 0.68 | SLC6A3 (0.40) | DRD4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8482364 | 0.66 | PDK1 (0.40) | DRD4DRD2DRD3CASR | |
| SCHEMBL8481920 | 0.65 | GRIN2B (0.45) | DRD4SIGMAR1 | |
| SCHEMBL28025079 | 0.64 | SLC1A3 (0.54) | SLC1A3SLC1A2SLC1A1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872117-A | TREATING CEREBROVASCULAR DEMENTIA, SENILE DEMENTIA, ALZHEIMER'S DEMENTIA, SEQUELAE OF ISCHEMIC ENCEPHALOPATHY AND CEREBRAL APOPLEXY | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-02-16 | — | — | US | disclosed |