Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8478531 | 0.78 | — | — | |
| SCHEMBL8477981 | 0.77 | MRGPRX4 (0.39) | RAB9ACYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL8477459 | 0.76 | OPRM1 (0.31) | — | |
| SCHEMBL6956503 | 0.74 | MEN1 (0.43) | NPC1RAB9ACYP1A2CYP2C19MEN1 | |
| SCHEMBL2560808 | 0.63 | ENPP2 (0.52) | NPC1RAB9ACYP1A2CYP2C19MEN1 | |
| SCHEMBL6953601 | 0.61 | ANO1 (0.44) | NPC1RAB9AALDH1A1SMN1; SMN2SLC6A4 | |
| SCHEMBL8592987 | 0.61 | NPC1 (0.46) | NPC1RAB9ACYP1A2CYP2C19MEN1 | |
| SCHEMBL17589345 | 0.60 | MRGPRX4 (0.66) | NPC1RAB9ACYP1A2CYP2C19MEN1 | |
| SCHEMBL22402260 | 0.59 | MRGPRX4 (0.45) | NPC1RAB9ACYP1A2CYP2C19MEN1 | |
| SCHEMBL1311327 | 0.59 | TSHR (0.50) | CYP1A2CYP2C19MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965740-A | POTENT FUNGICIDAL AND INSECTICIDAL ACTIVITY; LOW TOXICITY | SHIONOGI & CO., LTD. (JP) | 1999-10-12 | — | — | US | disclosed |