Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 2/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8484144 | 0.89 | KCNA3 (0.32) | NR3C2KCNA3KCNA5 | |
| SCHEMBL8669577 | 0.86 | NR3C2 (0.31) | NR3C2KCNA3KCNA5 | |
| SCHEMBL8504391 | 0.83 | NR3C2 (0.30) | NR3C2 | |
| SCHEMBL8479120 | 0.80 | POLB (0.34) | — | |
| SCHEMBL8663542 | 0.78 | POLB (0.34) | — | |
| SCHEMBL8486153 | 0.77 | — | — | |
| SCHEMBL8665948 | 0.75 | PGR (0.31) | — | |
| SCHEMBL8655292 | 0.74 | POLB (0.32) | — | |
| SCHEMBL8479793 | 0.74 | POLB (0.33) | — | |
| SCHEMBL8343961 | 0.72 | HCRTR2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883099-A | TREATMENT OF ATHERSCLEROSIS, PANCREATITIS OBESITY OR HYPERGLYCEMIA | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-16 | — | — | US | disclosed |
| US-5739135-A | PREVENTING OR TREATING ATHEROSCLEROSIS, PANCREATITIS SECONDARY TO HYPERTRIGLYCERIDEMIA, HYPERGLYCEMIA, OBESITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-14 | — | — | US | disclosed |