Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8504391 | 0.96 | NR3C2 (0.30) | NR3C2 | |
| SCHEMBL8484144 | 0.93 | KCNA3 (0.32) | NR3C2KCNA3KCNA5 | |
| SCHEMBL8482325 | 0.86 | NR3C2 (0.32) | NR3C2KCNA3KCNA5 | |
| SCHEMBL8663542 | 0.77 | POLB (0.34) | — | |
| SCHEMBL8665948 | 0.76 | PGR (0.31) | — | |
| SCHEMBL8479120 | 0.75 | POLB (0.34) | — | |
| SCHEMBL8486153 | 0.74 | — | — | |
| SCHEMBL8479793 | 0.70 | POLB (0.33) | — | |
| SCHEMBL8667893 | 0.69 | POLB (0.32) | — | |
| SCHEMBL8666560 | 0.69 | POLB (0.33) | JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827875-A | PYRROLIDINE DERIVATIVES; ANTIATHEROSCLEROSIS AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | disclosed |