SCHEMBL848301

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL849965	0.76	EGFR (0.36)	NOTUMMAPTLMNASMN1; SMN2HTT
	SCHEMBL28791227	0.75	HPGD (0.46)	MAPTLMNASMN1; SMN2MEN1KMT2A
	SCHEMBL28791233	0.73	HPGD (0.45)	MAPTLMNASMN1; SMN2MEN1KMT2A
	SCHEMBL3448675	0.73	ALDH1A1 (0.47)	MAPTLMNASMN1; SMN2MEN1KMT2A
	SCHEMBL1536726	0.72	AR (0.45)	NOTUMMAPTLMNASMN1; SMN2HTT
	SCHEMBL31622260	0.72	NOTUM (0.51)	NOTUMMAPTLMNASMN1; SMN2HTT
	SCHEMBL849876	0.72	MAPT (0.51)	NOTUMMAPTLMNASMN1; SMN2HTT
	SCHEMBL22288580	0.72	MEN1 (0.52)	NOTUMMAPTLMNASMN1; SMN2HTT
	SCHEMBL848300	0.70	MAPT (0.46)	NOTUMMAPTLMNASMN1; SMN2HTT
	SCHEMBL22288718	0.70	NOTUM (0.49)	NOTUMMAPTLMNASMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.