⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27906387 | 0.97 | — | — | |
| SCHEMBL27494523 | 0.74 | — | — | |
| SCHEMBL5490122 | 0.73 | — | — | |
| SCHEMBL26800848 | 0.73 | — | — | |
| Dimethylamine SCHEMBL4496394 | 0.70 | — | — | |
| SCHEMBL19881533 | 0.70 | ADRA2A (0.39) | — | |
| SCHEMBL25533401 | 0.69 | HRH3 (0.38) | — | |
| SCHEMBL8818411 | 0.69 | NPC1 (0.42) | — | |
| Hydrochloric Acid SCHEMBL28266031 | 0.67 | — | — | |
| Bromide SCHEMBL28268954 | 0.67 | ALDH1A1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | claimed |
| US-7297168-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2007-11-20 | — | — | US | claimed |
| US-7238212-B2 | Imidazole compounds and use of these compounds for dyeing keratinous fibers | L'OREAL, S.A. (FR) | 2007-07-03 | — | — | US | claimed |
| US-20050198745-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-09-15 | — | — | US | claimed |
| US-20050011019-A1 | Novel imidazole compounds and use of these compounds for dyeing keratinous fibers | L'OREAL, S.A. (FR) | 2005-01-20 | — | — | US | claimed |
| EP-1484049-A1 | Imidazole compounds and their use for dyeing of keratinous fibres | L'OREAL (FR) | 2004-12-08 | — | — | EP | claimed |
| US-12281101-B2 | Bicyclic lactams and methods of use thereof | GENENTECH, INC. (US) | 2025-04-22 | — | — | US | disclosed |
| CN-119775198-A | Cancer therapy targeting cancer stem cells | 治疗方案股份有限公司 | 2025-04-08 | — | — | CN | disclosed |
| CN-112312899-B | Cancer therapy targeting cancer stem cells | 治疗方案股份有限公司 | 2024-11-22 | — | — | CN | disclosed |
| EP-3760625-B1 | BICYCLIC LACTAMS AS RECEPTOR-INTERACTING PROTEIN-1 (RIP1) KINASE INHIBITORS FOR TREATING E.G. INFLAMMATORY DISEASES | HOFFMANN LA ROCHE (CH) | 2024-03-27 | — | — | EP | disclosed |
| CN-111269221-B | Bicyclic lactams and methods of use thereof | 豪夫迈·罗氏有限公司 | 2023-09-26 | — | — | CN | disclosed |
| CN-115916778-A | Methionine adenosyltransferase inhibitor, preparation method and application thereof | 赛诺哈勃药业（成都）有限公司 | 2023-04-04 | — | — | CN | disclosed |
| US-20220348559-A1 | BICYCLIC LACTAMS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2022-11-03 | — | — | US | disclosed |
| US-7297168-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2007-11-20 | — | — | US | disclosed |
| US-7238212-B2 | Imidazole compounds and use of these compounds for dyeing keratinous fibers | L'OREAL, S.A. (FR) | 2007-07-03 | — | — | US | disclosed |
| WO-2006128184-A2 | PYRIMIDINE OR TRIAZINE FUSED BICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS-PHARMACEUTICALS, INC. (US) | 2006-11-30 | — | — | WO | disclosed |
| US-20050198745-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-09-15 | — | — | US | disclosed |
| US-20050011019-A1 | Novel imidazole compounds and use of these compounds for dyeing keratinous fibers | L'OREAL, S.A. (FR) | 2005-01-20 | — | — | US | disclosed |
| EP-1484049-A1 | Imidazole compounds and their use for dyeing of keratinous fibres | L'OREAL (FR) | 2004-12-08 | — | — | EP | disclosed |
| US-4350804-A | Curable compositions comprising an azole-functional resin and a metal-ligand complex | PPG INDUSTRIES, INC. (US) | 1982-09-21 | — | — | US | disclosed |