Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 15/20 | 0.64 |
| ▸ | CAMKK1 | Q8N5S9 | 2/20 | 0.41 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL8485070 | 0.91 | LSS (0.71) | LSSCAMKK1CAMKK2 | |
| SCHEMBL8481533 | 0.82 | LSS (0.64) | LSSL3MBTL1 | |
| SCHEMBL8483781 | 0.82 | TLR8 (0.47) | LSSL3MBTL1 | |
| SCHEMBL8482625 | 0.80 | LSS (0.64) | LSSL3MBTL1 | |
| SCHEMBL8762179 | 0.78 | LSS (1.00) | LSS | |
| SCHEMBL8484681 | 0.78 | LSS (0.47) | LSSL3MBTL1 | |
| SCHEMBL21114055 | 0.75 | LSS (0.56) | LSSL3MBTL1 | |
| Fumaric Acid SCHEMBL8482421 | 0.74 | LSS (0.52) | LSS | |
| SCHEMBL8484083 | 0.74 | LSS (0.64) | LSSL3MBTL1 | |
| SCHEMBL8478959 | 0.74 | LSS (0.56) | LSSL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856503-A | ANTICHOLESTEROL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1999-01-05 | — | — | US | disclosed |