Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 16/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8481533 | 0.84 | LSS (0.64) | LSSL3MBTL1MAPT | |
| SCHEMBL8760843 | 0.79 | LSS (0.76) | LSS | |
| SCHEMBL8482625 | 0.78 | LSS (0.64) | LSSL3MBTL1 | |
| SCHEMBL8483576 | 0.78 | LSS (0.64) | LSSL3MBTL1 | |
| SCHEMBL7702285 | 0.76 | L3MBTL1 (0.51) | L3MBTL1 | |
| SCHEMBL7693885 | 0.76 | L3MBTL1 (0.51) | L3MBTL1 | |
| SCHEMBL7692562 | 0.76 | L3MBTL1 (0.51) | L3MBTL1 | |
| SCHEMBL7696748 | 0.76 | L3MBTL1 (0.51) | L3MBTL1 | |
| SCHEMBL8478959 | 0.75 | LSS (0.56) | LSSL3MBTL1MAPT | |
| SCHEMBL8483781 | 0.73 | TLR8 (0.47) | LSSL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856503-A | ANTICHOLESTEROL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1999-01-05 | — | — | US | disclosed |