SCHEMBL8484128

SCHEMBL8484128

CC(C)c1sc(F)c(N=C=O)c1Cl

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8602618 0.83 GABRA1 (0.30) GABRA1GABRB2
SCHEMBL8485659 0.77 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL3982730 0.69 GABRA1 (0.30) GABRA1GABRB2
SCHEMBL11481062 0.68
SCHEMBL8599752 0.68
SCHEMBL8603241 0.67
SCHEMBL22774480 0.67 CYP3A4 (0.32) GABRA1GABRB2
SCHEMBL8487778 0.67
SCHEMBL28419416 0.66 GABRA1 (0.36) GABRA1GABRB2
SCHEMBL9035934 0.65 HTT (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5883049-A Hydantoin derivatives and herbicides containing said derivatives as active ingredient SAGAMI CHEMICAL RESEARCH CENTER (JP) 1999-03-16 US disclosed
EP-0801068-A1 HYDANTOIN DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND HERBICIDES COMPRISING THE SAME AS ACTIVE INGREDIENTS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1997-10-15 EP disclosed