SCHEMBL9035934

SCHEMBL9035934

COC(=O)Cc1sc(F)c(N=C=O)c1Cl

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8601531 0.88 HTT (0.31) HTTHSD17B10
SCHEMBL7689951 0.81 HTT (0.31) HTTHSD17B10
SCHEMBL8604179 0.75 TRPM8 (0.33)
SCHEMBL8487778 0.72
SCHEMBL9074226 0.70
SCHEMBL8602852 0.70 GABRA1 (0.30)
SCHEMBL8485659 0.69 GABRA1 (0.33)
SCHEMBL8484128 0.65 GABRA1 (0.31)
SCHEMBL8736866 0.64 HSP90AB1 (0.37)
SCHEMBL9042780 0.64 SMN1; SMN2 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0408382-B1 Uracil derivatives and herbicides containing the same as active ingredient NISSAN CHEMICAL IND LTD (JP) 1996-09-18 EP disclosed
US-5127935-A Halogen, phenyl and heterocycle substituents, agricultural use NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1992-07-07 US disclosed
US-5084084-A Uracil and thiouracil derivatives NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1992-01-28 US disclosed
EP-0408382-A2 Uracil derivatives and herbicides containing the same as active ingredient NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1991-01-16 EP disclosed