SCHEMBL8484161

SCHEMBL8484161

CCCCOC(=O)COc1ccc(N=C=O)cc1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
PLA2G4B P0C869 5/20 0.47
CYP1A2 P05177 2/20 0.44
CYP2C19 P33261 2/20 0.44
PLA2G4A P47712 1/20 0.44
CYP3A4 P08684 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CYP19A1 P11511 1/20 0.43
CYP2C9 P11712 1/20 0.43
GAA P10253 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
PRSS1 P07477 1/20 0.43
ACR P10323 1/20 0.43
BLM P54132 1/20 0.43
PMP22 Q01453 1/20 0.43
HTT P42858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL832556 0.90 CYP3A4 (0.46) TDP1CYP1A2CYP2C19CYP3A4SMN1; SMN2
SCHEMBL414168 0.87 CYP1A2 (0.50) CYP1A2CYP2C19CYP3A4CYP19A1CYP2C9
SCHEMBL31338734 0.86 PPARG (0.41) ALDH1A1TDP1L3MBTL1PLA2G4BCYP1A2
SCHEMBL15910098 0.86 CYP3A4 (0.43) ALDH1A1TDP1CYP1A2CYP2C19CYP3A4
SCHEMBL863376 0.82 L3MBTL1 (0.47) ALDH1A1L3MBTL1GAA
SCHEMBL15371969 0.82 CYP3A4 (0.43) TDP1CYP1A2CYP2C19CYP3A4SMN1; SMN2
SCHEMBL11848774 0.82 NR5A1 (0.54) PLA2G4BPLA2G4AGAA
SCHEMBL3707532 0.82 NR5A1 (0.54) PLA2G4BPLA2G4AGAA
SCHEMBL1020538 0.82 NR5A1 (0.54) PLA2G4BPLA2G4AGAA
SCHEMBL7777016 0.82 NR5A1 (0.54) PLA2G4BPLA2G4AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5922717-A ANTICOAGULANTS DR. KARL THOMAE GMBH (DE) 1999-07-13 US disclosed