SCHEMBL863376

SCHEMBL863376

N#Cc1ccc(OCC(=O)OCCOC(=O)COc2ccc(N=C=O)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.47
MAPT P10636 2/20 0.47
ALDH1A1 P00352 1/20 0.47
MMP2 P08253 5/20 0.46
PPARD Q03181 2/20 0.45
PPARA Q07869 2/20 0.45
MMP3 P08254 5/20 0.43
MMP1 P03956 1/20 0.43
MMP9 P14780 1/20 0.43
MMP13 P45452 1/20 0.43
GAA P10253 1/20 0.41
KMT2A Q03164 1/20 0.41
HDAC1 Q13547 1/20 0.40
HDAC2 Q92769 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL832556 0.92 CYP3A4 (0.46) PPARDGAA
SCHEMBL9964592 0.88 CYP3A4 (0.39) L3MBTL1PPARDPPARAGAA
SCHEMBL15910098 0.87 CYP3A4 (0.43) ALDH1A1PPARDGAAKMT2A
SCHEMBL15908149 0.85 CYP1A2 (0.37) L3MBTL1PPARDPPARAGAA
SCHEMBL13624643 0.84 TDP1 (0.46) L3MBTL1MAPTALDH1A1PPARDPPARA
SCHEMBL15371969 0.84 CYP3A4 (0.43) PPARDPPARAGAA
SCHEMBL8484161 0.82 ALDH1A1 (0.47) L3MBTL1ALDH1A1GAA
SCHEMBL16270523 0.81 MEN1 (0.38) MAPTKMT2A
SCHEMBL830138 0.81 L3MBTL1 (0.41) L3MBTL1MAPTPPARAGAAKMT2A
SCHEMBL8708325 0.80 HDAC1 (0.56) L3MBTL1MAPTALDH1A1MMP2MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8143325-B2 Bioabsorbable and biocompatible polyurethanes and polyamides for medical devices BEZWADA BIOMEDICAL, LLC (US) 2012-03-27 US disclosed
US-20100260702-A1 BIOABSORBABLE AND BIOCOMPATIBLE POLYURETHANES AND POLYAMIDES FOR MEDICAL DEVICES BEZWADA BIOMEDICAL LLC (US) 2010-10-14 US disclosed
US-20100152272-A1 FUNCTIONALIZED DRUGS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2010-06-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100152272-A1 FUNCTIONALIZED DRUGS AND POLYMERS THEREFROM OGFR, LOX, DDO L3MBTL1 1729/4885MAPT 923/4885ALDH1A1 891/4885
US-20100260702-A1 BIOABSORBABLE AND BIOCOMPATIBLE POLYURETHANES AND POLYAMIDES FOR MEDICAL DEVICES ALOX12, HAO2, ALOX15 L3MBTL1 823/4885MAPT 3085/4885ALDH1A1 219/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.