Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.37 |
| ▸ | RELA | Q04206 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5775498 | 0.91 | CYP1A2 (0.41) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL30345337 | 0.88 | NPC1 (0.40) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL29760451 | 0.77 | CYP1A2 (0.46) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL2967279 | 0.75 | ADRA2A (0.34) | L3MBTL1TDP1NPC1NFKB1RAB9A | |
| SCHEMBL7759078 | 0.74 | KDM4E (0.51) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL29868676 | 0.74 | KDM4E (0.51) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL31173460 | 0.73 | KDM4E (0.41) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL4764699 | 0.73 | MEN1 (0.51) | CYP1A2CYP2D6CYP2C19KDM4EGLA | |
| SCHEMBL1009165 | 0.73 | MAOA (0.50) | KDM4EL3MBTL1TDP1GAAPARP1 | |
| SCHEMBL29405492 | 0.73 | MAOA (0.50) | KDM4EL3MBTL1TDP1GAAPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977134-A | Inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1999-11-02 | — | — | US | disclosed |