Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | CRHBP | P24387 | 1/20 | 0.64 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.56 |
| ▸ | BCL9 | O00512 | 1/20 | 0.56 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | HRH2 | P25021 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6335807 | 0.93 | MAPT (0.66) | MAPTCRHBPCRHR2L3MBTL1PTGS2 | |
| SCHEMBL16245527 | 0.92 | MAPT (0.68) | MAPTCRHBPCRHR2L3MBTL1PTGS2 | |
| SCHEMBL5467715 | 0.90 | MAPT (0.69) | MAPTCRHBPCRHR2L3MBTL1PTGS2 | |
| SCHEMBL17888638 | 0.87 | MAPT (0.59) | MAPTCRHBPCRHR2L3MBTL1PTGS2 | |
| SCHEMBL3026910 | 0.85 | PTGS2 (0.62) | MAPTCRHBPCRHR2L3MBTL1PTGS2 | |
| SCHEMBL656776 | 0.85 | PTGS2 (0.66) | MAPTCRHBPCRHR2L3MBTL1PTGS2 | |
| SCHEMBL21458578 | 0.83 | MAPT (0.58) | MAPTCRHBPCRHR2L3MBTL1PTGS2 | |
| SCHEMBL7640264 | 0.82 | MAPT (0.67) | MAPTCRHBPCRHR2L3MBTL1PTGS2 | |
| SCHEMBL9188865 | 0.81 | PTGS2 (0.61) | MAPTCRHBPCRHR2L3MBTL1PTGS2 | |
| Hydrochloric Acid SCHEMBL27483980 | 0.81 | MAPT (0.57) | MAPTCRHBPCRHR2L3MBTL1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922717-A | ANTICOAGULANTS | DR. KARL THOMAE GMBH (DE) | 1999-07-13 | — | — | US | disclosed |
| WO-1996020173-A1 | PIPERAZINE DERIVATIVES, MEDICAMENTS CONTAINING THE SAME, THEIR USE AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1996-07-04 | — | — | WO | disclosed |