Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | CRHBP | P24387 | 1/20 | 0.67 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | HRH2 | P25021 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | BCL9 | O00512 | 1/20 | 0.52 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16245527 | 0.99 | MAPT (0.68) | MAPTL3MBTL1CRHBPCRHR2ALDH1A1 | |
| SCHEMBL6335807 | 0.94 | MAPT (0.66) | MAPTL3MBTL1CRHBPCRHR2ALDH1A1 | |
| SCHEMBL6024458 | 0.91 | ALDH1A1 (0.62) | MAPTL3MBTL1CRHBPCRHR2ALDH1A1 | |
| SCHEMBL8484284 | 0.90 | MAPT (0.64) | MAPTL3MBTL1CRHBPCRHR2ALDH1A1 | |
| SCHEMBL17888638 | 0.88 | MAPT (0.59) | MAPTL3MBTL1CRHBPCRHR2ALDH1A1 | |
| SCHEMBL16261807 | 0.88 | MAPT (0.56) | MAPTL3MBTL1CRHBPCRHR2ALDH1A1 | |
| SCHEMBL831165 | 0.88 | MAPT (0.56) | MAPTL3MBTL1CRHBPCRHR2ALDH1A1 | |
| SCHEMBL7640264 | 0.86 | MAPT (0.67) | MAPTL3MBTL1CRHBPCRHR2ALDH1A1 | |
| SCHEMBL831490 | 0.86 | PTGS2 (0.58) | MAPTL3MBTL1CRHBPCRHR2ALDH1A1 | |
| SCHEMBL18689537 | 0.86 | PTGS2 (0.58) | MAPTL3MBTL1CRHBPCRHR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012170827-A2 | PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS | CYLENE PHARMACEUTICALS, INC. (US) | 2012-12-13 | — | — | WO | disclosed |
| WO-2012170827-A2 | PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS | CYLENE PHARMACEUTICALS, INC. (US) | 2012-12-13 | — | — | WO | disclosed |
| US-20070178544-A1 | Anti fk778antibodies and high sensitive immunoassay methods | TAMURA KOUICHI | 2007-08-02 | — | — | US | disclosed |
| EP-1723179-A1 | ANTI FK778 ANTIBODIES AND HIGH SENSITIVE IMMUNOASSAY METHODS | Astellas Pharma Inc. (JP) | 2006-11-22 | — | — | EP | disclosed |
| EP-1196545-B1 | ELECTRON DONOR SYSTEM FOR ENZYMES AND ITS USE FOR THE BIOCHEMICAL CONVERSION OF SUBSTRATES | BASF AG (DE) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005085290-A1 | ANTI FK778ANTIBODIES AND HIGH SENSITIVE IMMUNOASSAY METHODS | ASTELLAS PHARMA INC. (JP) | 2005-09-15 | — | — | WO | disclosed |
| EP-1196545-A1 | ELECTRON DONOR SYSTEM FOR ENZYMES AND ITS USE FOR THE BIOCHEMICAL CONVERSION OF SUBSTRATES | BASF AKTIENGESELLSCHAFT (DE) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001007573-A1 | ELECTRON DONOR SYSTEM FOR ENZYMES AND ITS USE FOR THE BIOCHEMICAL CONVERSION OF SUBSTRATES | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070178544-A1 | Anti fk778antibodies and high sensitive immunoassay methods | LY96, FAM83B, FAM162A | MAPT 4488/4885L3MBTL1 1380/4885CRHBP 936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.