Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Piperazinoacetate SCHEMBL5699 | 0.98 | SIGMAR1 (0.49) | SIGMAR1CHRM5CHRM3GSK3AGSK3B | |
| Ethyl Piperazinoacetate SCHEMBL16528281 | 0.96 | SIGMAR1 (0.47) | SIGMAR1CHRM5CHRM3GSK3AGSK3B | |
| Ethyl Piperazinoacetate SCHEMBL17271810 | 0.96 | SIGMAR1 (0.47) | SIGMAR1CHRM5CHRM3GSK3AGSK3B | |
| SCHEMBL8911402 | 0.96 | SIGMAR1 (0.47) | SIGMAR1CHRM5CHRM3GSK3AGSK3B | |
| SCHEMBL26091201 | 0.96 | SIGMAR1 (0.47) | SIGMAR1CHRM5CHRM3GSK3AGSK3B | |
| SCHEMBL31365998 | 0.93 | SIGMAR1 (0.43) | SIGMAR1CHRM5CHRM3GSK3AGSK3B | |
| SCHEMBL3684954 | 0.92 | SIGMAR1 (0.51) | SIGMAR1CHRM5CHRM3GSK3AGSK3B | |
| SCHEMBL1418858 | 0.91 | SIGMAR1 (0.54) | SIGMAR1CHRM5CHRM3GSK3AGSK3B | |
| Hydrochloric Acid SCHEMBL22344162 | 0.90 | SIGMAR1 (0.52) | SIGMAR1CHRM5CHRM3GSK3AGSK3B | |
| SCHEMBL4444447 | 0.89 | SIGMAR1 (0.51) | SIGMAR1CHRM5CHRM3ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113453720-B | Dual ligand drug conjugate and uses thereof | 同宜医药（苏州）有限公司 | 2025-05-06 | — | — | CN | disclosed |
| US-20220175761-A1 | BI-LIGAND DRUG CONJUGATE AND USE THEREOF | COHERENT BIOPHARMA SUZHOU LTD (CN) | 2022-06-09 | — | — | US | disclosed |
| US-5919431-A | 1,4,7,10-tetraazacyclododecane derivatives, their use, pharmaceutical agents containing these compounds and process for their production | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-07-06 | — | — | US | disclosed |
| EP-0730586-A1 | 1,4,7,10-TETRAAZACYCLODODECANE DERIVATIVES, THEIR USE, PHARMACEUTICALS CONTAINING THEM AND PROCESS FOR THEIR PRODUCTION | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-09-11 | — | — | EP | disclosed |
| WO-1995014678-A1 | 1,4,7,10-TETRAAZACYCLODODECANE DERIVATIVES, THEIR USE, PHARMACEUTICALS CONTAINING THEM AND PROCESS FOR THEIR PRODUCTION | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-06-01 | — | — | WO | disclosed |
| EP-0255471-B1 | 1,4,7,10-TETRAAZACYCLODODECANE-DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-09-09 | — | — | EP | disclosed |
| EP-0265247-A1 | Cyclopentyl ethers and their preparation and pharmaceutical formulation | GLAXO GROUP LIMITED (GB) | 1988-04-27 | — | — | EP | disclosed |
| EP-0255471-A1 | 1,4,7,10-Tetraazacyclododecane-derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-02-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220175761-A1 | BI-LIGAND DRUG CONJUGATE AND USE THEREOF | SLC10A1, CD47, SELPLG | SIGMAR1 1011/4885CHRM5 2221/4885CHRM3 2229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.