Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10375119 | 1.00 | FKBP1A (0.50) | FKBP1ACNR2ALDH1A1BCHEACHE | |
| SCHEMBL8483547 | 1.00 | FKBP1A (0.50) | FKBP1ACNR2ALDH1A1BCHEACHE | |
| SCHEMBL7459364 | 1.00 | FKBP1A (0.50) | FKBP1ACNR2ALDH1A1BCHEACHE | |
| SCHEMBL8483790 | 1.00 | FKBP1A (0.50) | FKBP1ACNR2ALDH1A1BCHEACHE | |
| SCHEMBL6586284 | 1.00 | FKBP1A (0.50) | FKBP1ACNR2ALDH1A1BCHEACHE | |
| SCHEMBL8484444 | 1.00 | FKBP1A (0.50) | FKBP1ACNR2ALDH1A1BCHEACHE | |
| SCHEMBL2310681 | 0.98 | FKBP1A (0.51) | FKBP1ACNR2ALDH1A1BCHEACHE | |
| SCHEMBL7028389 | 0.94 | CNR2 (0.50) | FKBP1ACNR2ALDH1A1BCHEACHE | |
| SCHEMBL9144282 | 0.92 | FKBP1A (0.44) | FKBP1ACNR2CYP24A1 | |
| SCHEMBL7402194 | 0.89 | MGLL (0.56) | CNR2BCHECA12CA9L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886007-A | USEFUL TO TREAT ALZHEIMER'S DISEASE WITH REDUCED SIDE EFFECT | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1999-03-23 | — | — | US | disclosed |
| US-5783584-A | USEFUL IN THE TREATMENT OF ALZHEIMER'S DISEASE | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1998-07-21 | — | — | US | disclosed |
| EP-0606090-B1 | Mesomorphic compound, liquid crystal composition containing same, and liquid crystal device using same | CANON KK (JP) | 1997-10-29 | — | — | EP | disclosed |
| WO-1997021681-A1 | THA ANALOGS USEFUL AS CHOLINESTERASE INHIBITORS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1997-06-19 | — | — | WO | disclosed |
| US-5589103-A | Mesomorphic compound, liquid crystal composition containing same, and liquid crystal device using same | CANON KABUSHIKI KAISHA (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0606090-A1 | Mesomorphic compound, liquid crystal composition containing same, and liquid crystal device using same | CANON KABUSHIKI KAISHA (JP) | 1994-07-13 | — | — | EP | disclosed |