SCHEMBL8485037

SCHEMBL8485037

CC=CCN(C)Oc1ccc2c(-c3ccc(Br)cc3)nccc2c1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LSS P48449 17/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8481535 0.80 LSS (0.61) LSS
SCHEMBL8485030 0.78 LSS (0.49) LSS
SCHEMBL8484409 0.76 LSS (0.55) LSS
SCHEMBL8484786 0.75 LSS (0.71) LSS
SCHEMBL8484785 0.75 LSS (0.71) LSS
SCHEMBL8485034 0.72 LSS (0.52) LSS
SCHEMBL8760752 0.72 LSS (1.00) LSS
SCHEMBL8478588 0.70 LSS (0.66) LSS
SCHEMBL8483929 0.70 LSS (0.58) LSS
SCHEMBL8481533 0.69 LSS (0.64) LSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5856503-A ANTICHOLESTEROL AGENTS HOFFMANN-LA ROCHE INC. (US) 1999-01-05 US disclosed