Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 10/20 | 0.49 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8481531 | 0.81 | LSS (0.50) | LSS | |
| SCHEMBL8485037 | 0.78 | LSS (0.56) | LSS | |
| SCHEMBL8484409 | 0.76 | LSS (0.55) | LSSMEN1KMT2A | |
| SCHEMBL8485034 | 0.72 | LSS (0.52) | LSS | |
| SCHEMBL8478710 | 0.70 | LSS (0.46) | LSS | |
| SCHEMBL8478588 | 0.70 | LSS (0.66) | LSSMEN1KMT2A | |
| SCHEMBL8481533 | 0.69 | LSS (0.64) | LSSMEN1KMT2A | |
| SCHEMBL8483926 | 0.69 | LSS (0.52) | LSS | |
| SCHEMBL8484786 | 0.69 | LSS (0.71) | LSS | |
| SCHEMBL8760852 | 0.69 | LSS (0.55) | LSSMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856503-A | ANTICHOLESTEROL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1999-01-05 | — | — | US | disclosed |