Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8483968 | 0.83 | TSHR (0.57) | ALDH1A1LMNATSHRMAPK10KDM4E | |
| SCHEMBL2093835 | 0.82 | ALDH1A1 (0.64) | ALDH1A1LMNATSHRMAPK8MAPK9 | |
| SCHEMBL996466 | 0.81 | ALDH1A1 (0.50) | ALDH1A1LMNATSHRMAPK8MAPK9 | |
| SCHEMBL8478378 | 0.81 | ALDH1A1 (0.50) | ALDH1A1LMNATSHRMAPK8MAPK9 | |
| SCHEMBL16957659 | 0.81 | ALDH1A1 (0.50) | ALDH1A1LMNATSHRMAPK8MAPK9 | |
| SCHEMBL16955180 | 0.79 | LMNA (0.49) | ALDH1A1LMNATSHRMAPK8MAPK9 | |
| SCHEMBL2619294 | 0.79 | MRGPRX4 (0.50) | ALDH1A1LMNATSHRMAPK8MAPK9 | |
| SCHEMBL16952642 | 0.79 | ALDH1A1 (0.49) | ALDH1A1LMNATSHRMAPK8MAPK9 | |
| SCHEMBL4326103 | 0.79 | ALDH1A1 (0.49) | ALDH1A1LMNATSHRMAPK8MAPK9 | |
| SCHEMBL6828111 | 0.79 | ALDH1A1 (0.49) | ALDH1A1LMNATSHRMAPK8MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856334-A | ANTAGONIST FOR EOSINOPHILS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-05 | — | — | US | disclosed |
| EP-0773219-A1 | IMIDAZOQUINOLINE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-14 | — | — | EP | disclosed |