SCHEMBL8485336

SCHEMBL8485336

CC1CC(=O)NCC(C)(C)C1

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.48
ALDH1A1 P00352 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.38
BRD4 O60885 1/20 0.34
CREBBP Q92793 1/20 0.34
GAA P10253 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31681117 0.78 SMN1; SMN2 (0.36) CRBNSMN1; SMN2
SCHEMBL8550115 0.74 CRBN (0.52) CRBNALDH1A1SMN1; SMN2BRD4CREBBP
SCHEMBL28569512 0.70 SMN1; SMN2 (0.34) ALDH1A1SMN1; SMN2
SCHEMBL25138031 0.68 CRBN (0.56) CRBNALDH1A1BRD4CREBBP
SCHEMBL248285 0.67
SCHEMBL10196459 0.67
SCHEMBL8271926 0.67
SCHEMBL1936620 0.67
SCHEMBL24862 0.67 ALDH1A1 (0.42) CRBNALDH1A1SMN1; SMN2GAATDP1
SCHEMBL4868570 0.67 ALDH1A1 (0.42) CRBNALDH1A1SMN1; SMN2GAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5986092-A DEHYDROHALOGENATION, BASIFICATION AND PHASE TRANSFER CATALYST SNPE (FR) 1999-11-16 US claimed
US-5986092-A DEHYDROHALOGENATION, BASIFICATION AND PHASE TRANSFER CATALYST SNPE (FR) 1999-11-16 US disclosed