Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 12/20 | 0.74 |
| ▸ | ADAMTS4 | O75173 | 4/20 | 0.74 |
| ▸ | MMP13 | P45452 | 3/20 | 0.74 |
| ▸ | MMP8 | P22894 | 2/20 | 0.74 |
| ▸ | MMP2 | P08253 | 15/20 | 0.71 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.63 |
| ▸ | MMP1 | P03956 | 1/20 | 0.63 |
| ▸ | MMP3 | P08254 | 1/20 | 0.63 |
| ▸ | MMP7 | P09237 | 1/20 | 0.63 |
| ▸ | MMP12 | P39900 | 1/20 | 0.61 |
| ▸ | MMP14 | P50281 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8492008 | 1.00 | MMP9 (0.74) | MMP9ADAMTS4MMP13MMP8MMP2 | |
| SCHEMBL698080 | 0.92 | MMP9 (0.61) | MMP9ADAMTS4MMP13MMP8MMP2 | |
| SCHEMBL713304 | 0.92 | MMP9 (0.61) | MMP9ADAMTS4MMP13MMP8MMP2 | |
| SCHEMBL698079 | 0.92 | MMP9 (0.61) | MMP9ADAMTS4MMP13MMP8MMP2 | |
| SCHEMBL7680612 | 0.90 | MMP2 (0.70) | MMP9ADAMTS4MMP13MMP8MMP2 | |
| SCHEMBL7680606 | 0.90 | MMP2 (0.70) | MMP9ADAMTS4MMP13MMP8MMP2 | |
| SCHEMBL14602257 | 0.86 | MMP9 (0.56) | MMP9ADAMTS4MMP13MMP8MMP2 | |
| SCHEMBL14602271 | 0.85 | MMP9 (1.00) | MMP9ADAMTS4MMP13MMP8MMP2 | |
| SCHEMBL31609930 | 0.85 | MMP9 (1.00) | MMP9ADAMTS4MMP13MMP8MMP2 | |
| SCHEMBL14602275 | 0.85 | MMP9 (1.00) | MMP9ADAMTS4MMP13MMP8MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160903-B2 | Sulfonylaminocarboxylic acids | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-01-09 | — | — | US | disclosed |
| US-7160903-B2 | Sulfonylaminocarboxylic acids | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-01-09 | — | — | US | disclosed |
| EP-0877018-B1 | Sulfonylaminocarboxylic acids | AVENTIS PHARMA GMBH (DE) | 2003-05-02 | — | — | EP | disclosed |