Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 4/20 | 0.66 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | F2 | P00734 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663879 | 0.79 | KCNJ1 (1.00) | KCNJ1NOTUMMAPTF2ALDH1A1 | |
| SCHEMBL10738426 | 0.78 | NOTUM (1.00) | KCNJ1NOTUMMAPTF2ALDH1A1 | |
| SCHEMBL1163779 | 0.78 | NOTUM (0.64) | KCNJ1NOTUMMAPTF2ALDH1A1 | |
| SCHEMBL311636 | 0.78 | MAPT (1.00) | KCNJ1NOTUMMAPTF2ALDH1A1 | |
| SCHEMBL82595 | 0.78 | MAPT (0.69) | KCNJ1NOTUMMAPTF2ALDH1A1 | |
| SCHEMBL11716535 | 0.77 | NOTUM (0.62) | KCNJ1NOTUMMAPTF2ALDH1A1 | |
| SCHEMBL14919144 | 0.76 | NOTUM (0.61) | KCNJ1NOTUMMAPTF2ALDH1A1 | |
| SCHEMBL334399 | 0.76 | KCNJ1 (1.00) | KCNJ1NOTUMMAPTF2ALDH1A1 | |
| SCHEMBL3962509 | 0.76 | NOTUM (0.95) | KCNJ1NOTUMMAPTF2ALDH1A1 | |
| SCHEMBL7096356 | 0.76 | NOTUM (0.95) | KCNJ1NOTUMMAPTF2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877196-A | N- 4-(imidazolyl or pyrazolyl)phenyl(oxy, sulfinyl, sulfenyl or sulfonyl)alkyl!carboxamides, sulfonamides or phosphoramides having antiarrhythmic properties | AMERICAN CYANAMID COMPANY (US) | 1999-03-02 | — | — | US | disclosed |