Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603166 | 0.83 | — | — | |
| SCHEMBL8484124 | 0.83 | MAPK1 (0.31) | TDP1MAPK1 | |
| SCHEMBL1100652 | 0.80 | TDP1 (0.33) | TDP1MAPK1CYP3A4TRPA1ALDH1A1 | |
| SCHEMBL7931545 | 0.80 | TDP1 (0.45) | TDP1MAPK1CYP3A4TRPA1ALDH1A1 | |
| SCHEMBL10347965 | 0.78 | TDP1 (0.39) | TDP1MAPK1CYP3A4TRPA1ALDH1A1 | |
| SCHEMBL8486447 | 0.78 | — | — | |
| SCHEMBL9836795 | 0.77 | CYP3A4 (0.42) | TDP1MAPK1CYP3A4TRPA1ALDH1A1 | |
| SCHEMBL8487776 | 0.77 | HTR2A (0.30) | — | |
| SCHEMBL8481186 | 0.76 | — | — | |
| SCHEMBL8485879 | 0.76 | CA12 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883049-A | Hydantoin derivatives and herbicides containing said derivatives as active ingredient | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1999-03-16 | — | — | US | disclosed |
| EP-0801068-A1 | HYDANTOIN DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND HERBICIDES COMPRISING THE SAME AS ACTIVE INGREDIENTS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1997-10-15 | — | — | EP | disclosed |