SCHEMBL8484124

SCHEMBL8484124

CC(C)Sc1cc(N=C=O)c(F)cc1Cl

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
KCNQ3 O43525 1/20 0.30
KCNQ2 O43526 1/20 0.30
KCNE1 P15382 1/20 0.30
KCNQ1 P51787 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8486447 0.86
SCHEMBL8602612 0.85
SCHEMBL8485658 0.83 TDP1 (0.33) MAPK1TDP1
SCHEMBL9851164 0.82
SCHEMBL9569006 0.80 MAPT (0.37) TDP1
SCHEMBL27360152 0.76 TDP1 (0.33) MAPK1TDP1
SCHEMBL7931545 0.76 TDP1 (0.45) MAPK1TDP1
SCHEMBL10347965 0.75 TDP1 (0.39) MAPK1TDP1
SCHEMBL9836795 0.74 CYP3A4 (0.42) MAPK1TDP1
SCHEMBL8487776 0.74 HTR2A (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5883049-A Hydantoin derivatives and herbicides containing said derivatives as active ingredient SAGAMI CHEMICAL RESEARCH CENTER (JP) 1999-03-16 US disclosed
EP-0801068-A1 HYDANTOIN DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND HERBICIDES COMPRISING THE SAME AS ACTIVE INGREDIENTS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1997-10-15 EP disclosed