Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 0.71 |
| ▸ | NPC1 | O15118 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30255067 | 1.00 | MAOA (0.71) | MAOANPC1MEN1KMT2AABCG2 | |
| SCHEMBL28205926 | 0.85 | MAOA (0.58) | MAOANPC1MEN1KMT2AABCG2 | |
| SCHEMBL5612997 | 0.85 | MAOA (0.69) | MAOANPC1MEN1KMT2AABCG2 | |
| SCHEMBL30255441 | 0.85 | MAOA (0.69) | MAOANPC1MEN1KMT2AABCG2 | |
| SCHEMBL21912642 | 0.84 | MAOA (0.65) | MAOANPC1MEN1KMT2AABCG2 | |
| SCHEMBL14252988 | 0.83 | ALDH1A1 (0.65) | MAOANPC1MEN1KMT2AABCG2 | |
| SCHEMBL29711224 | 0.82 | MGAM (0.64) | MAOAMEN1KMT2AABCG2KDM4E | |
| SCHEMBL31378227 | 0.82 | MGAM (0.64) | MAOAMEN1KMT2AABCG2KDM4E | |
| SCHEMBL12500715 | 0.81 | MAOA (0.64) | MAOANPC1MEN1KMT2AKDM4E | |
| SCHEMBL30346289 | 0.80 | MAOA (0.65) | MAOANPC1MEN1KMT2AABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104650024-B | The purposes of biological species mouth mountain ketone monomeric compound anti-hepatic fibrosis and hepatic sclerosis | 北京大学 | 2018-04-27 | — | — | CN | disclosed |
| CN-107297128-A | Can the new decorating house of fast purification air freshener | 王婧宁 | 2017-10-27 | — | — | CN | disclosed |
| CN-104936626-A | Coating for substrate | GORE & ASS | 2015-09-23 | — | — | CN | disclosed |
| CN-103655689-A | Method for preparing lamiophlomis rotata extract | JIANGXI NANCHANG PHARMACEUTICAL CO LTD | 2014-03-26 | — | — | CN | disclosed |
| CN-102212067-B | Garcinia derivative, method for preparing same and pharmaceutical application thereof | UNIV CHINA PHARMA | 2013-01-30 | — | — | CN | disclosed |
| CN-102138965-B | Halenia elliptica D.Don extract and preparation method, pharmaceutical composition and application thereof | TIANJIN INST PHARM RESEARCH | 2012-12-19 | — | — | CN | disclosed |
| CN-102212067-A | Garcinia derivative, method for preparing same and pharmaceutical application thereof | UNIV CHINA PHARMA | 2011-10-12 | — | — | CN | disclosed |
| CN-102138965-A | Halenia elliptica D.Don extract and preparation method, pharmaceutical composition and application thereof | TIANJIN INST PHARM RESEARCH | 2011-08-03 | — | — | CN | disclosed |
| US-5981774-A | PREPARING 3,5-DI(2,3-EPOXYPROPOXY)-1-HYDROXYXANTHONE BY REACTING 1,3,5-TRIMETHOXYXANTHONE WITH HYDROGEN IODIDE IN PHENOL WHEREBY 1,3,5-TRIHYDROXYXANTHONE IS OBTAINED, REACTING PRODUCT WITH EPICHLOROHYDRIN IN POTASSIUM HYDROXIDE | NATIONAL SCIENCE COUNCIL (TW) | 1999-11-09 | — | — | US | disclosed |
| US-5741813-A | ADMINISTERING SUBSTITUTED XANTHONES | NATIONAL SCIENCE COUNCIL (TW) | 1998-04-21 | — | — | US | disclosed |