Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 5/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485812 | 1.00 | PREP (0.56) | PREPGFERCTRB1TSHRALDH1A1 | |
| SCHEMBL8479441 | 0.79 | RIPK1 (0.39) | TSHRALDH1A1 | |
| SCHEMBL28367 | 0.79 | L3MBTL1 (0.67) | PREPCTRB1TSHRALDH1A1NPSR1 | |
| SCHEMBL2733159 | 0.79 | L3MBTL1 (0.67) | PREPCTRB1TSHRALDH1A1NPSR1 | |
| SCHEMBL11262909 | 0.78 | PREP (0.69) | PREPGFERCTRB1TSHRNPSR1 | |
| SCHEMBL11262912 | 0.78 | PREP (0.69) | PREPGFERCTRB1TSHRNPSR1 | |
| SCHEMBL16750358 | 0.78 | PREP (0.58) | PREPCTRB1TSHRALDH1A1NPSR1 | |
| SCHEMBL488744 | 0.77 | PREP (0.68) | PREPCTRB1TSHRNPSR1L3MBTL1 | |
| SCHEMBL6384850 | 0.77 | PREP (0.68) | PREPCTRB1TSHRNPSR1L3MBTL1 | |
| SCHEMBL18093534 | 0.77 | PREP (0.71) | PREPGFERCTRB1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5936098-A | Process for producing indoline compounds and intermediates for the production of the same | TOKYO TANABE COMPANY LIMITED (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0810214-A1 | PROCESS FOR PRODUCING INDOLINE COMPOUNDS AND INTERMEDIATES FOR THE PRODUCTION OF THE SAME | TOKYO TANABE COMPANY LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |